E15K (p.Glu15Lys) variant of BCL2L11 (Bcl-2-like protein 11)
E15K (p.Glu15Lys) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
E15K (p.Glu15Lys) variant details
- p.Glu15Lys
- ExAC rs776207874
- TOPMed rs776207874
- gnomAD rs776207874
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.27
- MetaLR 0.26
- MetaSVM -0.53
- CADD 29.80
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available