C12F (p.Cys12Phe) variant of BCL2L11 (Bcl-2-like protein 11)
C12F (p.Cys12Phe) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
C12F (p.Cys12Phe) variant details
- p.Cys12Phe
- gnomAD 2-111123780-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.677
- REVEL 0.70
- MetaLR 0.26
- MetaSVM -0.52
- CADD 28.40
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available