A32D (p.Ala32Asp) variant of BCL2L11 (Bcl-2-like protein 11)
A32D (p.Ala32Asp) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
A32D (p.Ala32Asp) variant details
- p.Ala32Asp
- gnomAD 2-111123840-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.527
- REVEL 0.41
- MetaLR 0.27
- MetaSVM -0.52
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available