A2G (p.Ala2Gly) variant of BCL2L11 (Bcl-2-like protein 11)
A2G (p.Ala2Gly) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
A2G (p.Ala2Gly) variant details
- p.Ala2Gly
- ExAC rs756367205
- gnomAD rs756367205
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.24
- MetaLR 0.26
- MetaSVM -0.52
- CADD 26.80
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available