A22E (p.Ala22Glu) variant of BCL2L11 (Bcl-2-like protein 11)
A22E (p.Ala22Glu) in BCL2L11 (Bcl-2-like protein 11) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A22E (p.Ala22Glu) variant details
- p.Ala22Glu
- gnomAD rs1429573443
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.11
- MetaLR 0.16
- MetaSVM -0.71
- CADD 21.90
- PolyPhen-2 0.24
- SIFT 0.01
- Population evidence available
- Structural context available