S4I (p.Ser4Ile) variant of BCL2L1 (Bcl-2-like protein 1)
S4I (p.Ser4Ile) in BCL2L1 (Bcl-2-like protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S4I (p.Ser4Ile) variant details
- p.Ser4Ile
- gnomAD 20-31722208-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.16
- MetaLR 0.05
- MetaSVM -1.18
- CADD 23.40
- PolyPhen-2 0.94
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available