R6L (p.Arg6Leu) variant of BCL2L1 (Bcl-2-like protein 1)
R6L (p.Arg6Leu) in BCL2L1 (Bcl-2-like protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R6L (p.Arg6Leu) variant details
- p.Arg6Leu
- 1000Genomes rs148274815
- ESP rs148274815
- ExAC rs148274815
- TOPMed rs148274815
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.36
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 7.2e-05)
- Structural context available