R34K (p.Arg34Lys) variant of BCL2L1 (Bcl-2-like protein 1)
R34K (p.Arg34Lys) in BCL2L1 (Bcl-2-like protein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R34K (p.Arg34Lys) variant details
- p.Arg34Lys
- ExAC rs773505559
- TOPMed rs773505559
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.04
- CADD 22.90
- PolyPhen-2 0.22
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 5.3e-05)
- Structural context available