Y9H (p.Tyr9His) variant of BCL2 (Apoptosis regulator Bcl-2)
Y9H (p.Tyr9His) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
Y9H (p.Tyr9His) variant details
- p.Tyr9His
- cosmic curated COSV61382
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.28
- MetaLR 0.04
- MetaSVM -1.17
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available