P39A (p.Pro39Ala) variant of BCL2 (Apoptosis regulator Bcl-2)
P39A (p.Pro39Ala) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
P39A (p.Pro39Ala) variant details
- p.Pro39Ala
- cosmic curated COSV10520
- Missense
- Variant Prioritization Score for Impact Estimate 0.0639
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.98
- CADD 0.28
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available