M16T (p.Met16Thr) variant of BCL2 (Apoptosis regulator Bcl-2)
M16T (p.Met16Thr) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
M16T (p.Met16Thr) variant details
- p.Met16Thr
- cosmic curated COSV10520
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.08
- MetaLR 0.01
- MetaSVM -1.00
- CADD 22.00
- PolyPhen-2 0.20
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available