L23L (p.Leu23Leu) variant of BCL2 (Apoptosis regulator Bcl-2)
L23L (p.Leu23Leu) in BCL2 (Apoptosis regulator Bcl-2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L23L (p.Leu23Leu) variant details
- p.Leu23Leu
- rs1178177633
- gnomAD 18-63318598-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.465
- CADD 14.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available