G36V (p.Gly36Val) variant of BCL2 (Apoptosis regulator Bcl-2)
G36V (p.Gly36Val) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
G36V (p.Gly36Val) variant details
- p.Gly36Val
- gnomAD 18-63318560-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.04
- MetaLR 0.01
- MetaSVM -0.98
- CADD 11.40
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 7.1e-05)
- Structural context available
- Literature evidence available