G36S (p.Gly36Ser) variant of BCL2 (Apoptosis regulator Bcl-2)
G36S (p.Gly36Ser) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
G36S (p.Gly36Ser) variant details
- p.Gly36Ser
- gnomAD 18-63318561-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.96
- CADD 10.50
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available