A37V (p.Ala37Val) variant of BCL2 (Apoptosis regulator Bcl-2)
A37V (p.Ala37Val) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A37V (p.Ala37Val) variant details
- p.Ala37Val
- cosmic curated COSV61377
- Ensembl rs2144325609
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.08
- MetaLR 0.01
- MetaSVM -0.98
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available