A37T (p.Ala37Thr) variant of BCL2 (Apoptosis regulator Bcl-2)
A37T (p.Ala37Thr) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A37T (p.Ala37Thr) variant details
- p.Ala37Thr
- Ensembl rs1913584363
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.04
- MetaLR 0.01
- MetaSVM -0.96
- CADD 14.20
- PolyPhen-2 0.09
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available