A32S (p.Ala32Ser) variant of BCL2 (Apoptosis regulator Bcl-2)
A32S (p.Ala32Ser) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
A32S (p.Ala32Ser) variant details
- p.Ala32Ser
- gnomAD 18-63318573-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.06
- MetaLR 0.01
- MetaSVM -0.92
- CADD 11.00
- PolyPhen-2 0.03
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available