A32P (p.Ala32Pro) variant of BCL2 (Apoptosis regulator Bcl-2)
A32P (p.Ala32Pro) in BCL2 (Apoptosis regulator Bcl-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A32P (p.Ala32Pro) variant details
- p.Ala32Pro
- ExAC rs760840889
- gnomAD rs760840889
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.16
- MetaLR 0.02
- MetaSVM -0.94
- CADD 19.00
- PolyPhen-2 0.59
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available