V74A (p.Val74Ala) variant of BAK1 (Q16611)
V74A (p.Val74Ala) in BAK1 (Q16611) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V74A (p.Val74Ala) variant details
- p.Val74Ala
- ExAC rs755256768
- gnomAD rs755256768
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.18
- CADD 28.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available