E25K (p.Glu25Lys) variant of BAK1 (Q16611)
E25K (p.Glu25Lys) in BAK1 (Q16611) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E25K (p.Glu25Lys) variant details
- p.Glu25Lys
- gnomAD rs1307766428
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.04
- CADD 23.00
- PolyPhen-2 0.06
- SIFT 0.15
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available