W26L (p.Trp26Leu) variant of BAG3 (O95817)
W26L (p.Trp26Leu) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
W26L (p.Trp26Leu) variant details
- p.Trp26Leu
- gnomAD 10-119651752-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.869
- REVEL 0.93
- CADD 31.00
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- BAG3 WW domain domainome 1.0: score 1.02
- Literature evidence available