W26C (p.Trp26Cys) variant of BAG3 (O95817)
W26C (p.Trp26Cys) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
W26C (p.Trp26Cys) variant details
- p.Trp26Cys
- gnomAD 10-119651753-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.90
- CADD 27.20
- PolyPhen-2 0.31
- SIFT 0.00
- Population evidence available
- Structural context available
- BAG3 WW domain domainome 1.0: score 1.02
- Literature evidence available