P37T (p.Pro37Thr) variant of BAG3 (O95817)
P37T (p.Pro37Thr) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P37T (p.Pro37Thr) variant details
- p.Pro37Thr
- gnomAD 10-119651784-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.688
- REVEL 0.64
- CADD 26.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.108
- Literature evidence available