P32S (p.Pro32Ser) variant of BAG3 (O95817)
P32S (p.Pro32Ser) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P32S (p.Pro32Ser) variant details
- p.Pro32Ser
- gnomAD 10-119651769-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.642
- REVEL 0.56
- CADD 26.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.55
- Literature evidence available