P21P (p.Pro21Pro) variant of BAG3 (O95817)
P21P (p.Pro21Pro) in BAG3 (O95817) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P21P (p.Pro21Pro) variant details
- p.Pro21Pro
- gnomAD 10-119651738-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.197
- CADD 11.90
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- BAG3 WW domain domainome 1.0: score -1.1
- Literature evidence available