P21H (p.Pro21His) variant of BAG3 (O95817)
P21H (p.Pro21His) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P21H (p.Pro21His) variant details
- p.Pro21His
- gnomAD 10-119651737-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.64
- CADD 26.40
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- BAG3 WW domain domainome 1.0: score -1.1
- Literature evidence available