N16S (p.Asn16Ser) variant of BAG3 (O95817)
N16S (p.Asn16Ser) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
N16S (p.Asn16Ser) variant details
- p.Asn16Ser
- gnomAD 10-119651722-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.09
- CADD 18.70
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.326
- Literature evidence available