G35A (p.Gly35Ala) variant of BAG3 (O95817)
G35A (p.Gly35Ala) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G35A (p.Gly35Ala) variant details
- p.Gly35Ala
- gnomAD 10-119651779-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.843
- REVEL 0.90
- CADD 28.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.229
- Literature evidence available