G17S (p.Gly17Ser) variant of BAG3 (O95817)
G17S (p.Gly17Ser) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G17S (p.Gly17Ser) variant details
- p.Gly17Ser
- gnomAD 10-119651724-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.15
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.05
- Population evidence available
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.795
- Literature evidence available