G17D (p.Gly17Asp) variant of BAG3 (O95817)
G17D (p.Gly17Asp) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G17D (p.Gly17Asp) variant details
- p.Gly17Asp
- gnomAD 10-119651725-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.14
- CADD 23.70
- PolyPhen-2 0.14
- SIFT 0.01
- Population evidence available
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.795
- Literature evidence available