G15S (p.Gly15Ser) variant of BAG3 (O95817)
G15S (p.Gly15Ser) in BAG3 (O95817) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G15S (p.Gly15Ser) variant details
- p.Gly15Ser
- ExAC rs768378511
- gnomAD rs768378511
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.12
- CADD 22.80
- PolyPhen-2 0.10
- SIFT 0.23
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available
- BAG3 WW domain domainome 1.0: score -0.0966