R4W (p.Arg4Trp) variant of AXL (P30530)
R4W (p.Arg4Trp) in AXL (P30530) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
R4W (p.Arg4Trp) variant details
- p.Arg4Trp
- cosmic curated COSV10737
- 1000Genomes rs182481095
- ExAC rs182481095
- TOPMed rs182481095
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.16
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the HGDP:NAXI population (allele frequency 0.071)
- Structural context available