G21S (p.Gly21Ser) variant of AXL (P30530)
G21S (p.Gly21Ser) in AXL (P30530) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G21S (p.Gly21Ser) variant details
- p.Gly21Ser
- ExAC rs778406577
- gnomAD rs778406577
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.09
- CADD 15.40
- PolyPhen-2 0.04
- SIFT 0.37
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available