C24W (p.Cys24Trp) variant of AXL (P30530)
C24W (p.Cys24Trp) in AXL (P30530) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
C24W (p.Cys24Trp) variant details
- p.Cys24Trp
- TOPMed rs1389617751
- gnomAD rs1389617751
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.27
- CADD 16.50
- PolyPhen-2 0.69
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available