T87I (p.Thr87Ile) variant of ATRX (Chromatin remodeler ATRX)
T87I (p.Thr87Ile) in ATRX (Chromatin remodeler ATRX) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
T87I (p.Thr87Ile) variant details
- p.Thr87Ile
- Ensembl rs2072205781
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.63
- ESM-1b 0.00
- AlphaMissense 0.71
- CADD 23.60
- PolyPhen-2 0.99
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available