V73L (p.Val73Leu) variant of ATP6V1A (P38606)
V73L (p.Val73Leu) in ATP6V1A (P38606) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
V73L (p.Val73Leu) variant details
- p.Val73Leu
- TOPMed rs981146211
- gnomAD rs981146211
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.36
- AlphaMissense 0.34
- MetaLR 0.23
- MetaSVM -0.70
- CADD 20.80
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available