A22T (p.Ala22Thr) variant of ATP6V0A4 (Q9HBG4)
A22T (p.Ala22Thr) in ATP6V0A4 (Q9HBG4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- rs1393351118
- TOPMed rs1393351118
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.785
- ESM-1b 1.00
- AlphaMissense 0.37
- MetaLR 0.82
- MetaSVM 0.94
- PolyPhen-2 0.97
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available