P87A (p.Pro87Ala) variant of ATP1A1 (P05023)
P87A (p.Pro87Ala) in ATP1A1 (P05023) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
P87A (p.Pro87Ala) variant details
- p.Pro87Ala
- ExAC rs749401049
- TOPMed rs749401049
- gnomAD rs749401049
- Missense
- Variant Prioritization Score for Impact Estimate 0.789
- REVEL 0.79
- MetaLR 0.78
- MetaSVM 0.74
- CADD 24.50
- PolyPhen-2 0.76
- SIFT 0.00
- Most common in the HGDP:MANDENKA population (allele frequency 0.33)
- Structural context available