S24N (p.Ser24Asn) variant of ASIC1 (Acid-sensing ion channel 1)
S24N (p.Ser24Asn) in ASIC1 (Acid-sensing ion channel 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S24N (p.Ser24Asn) variant details
- p.Ser24Asn
- gnomAD rs1218229701
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.15
- MetaLR 0.10
- MetaSVM -1.02
- CADD 22.10
- Most common in the African/African-American population (allele frequency 0.00046)
- Structural context available