F21S (p.Phe21Ser) variant of ASIC1 (Acid-sensing ion channel 1)
F21S (p.Phe21Ser) in ASIC1 (Acid-sensing ion channel 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
F21S (p.Phe21Ser) variant details
- p.Phe21Ser
- gnomAD 12-50073616-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.16
- ESM-1b 1.00
- AlphaMissense 1.00
- CADD 18.20
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available