I37S (p.Ile37Ser) variant of ARID2 (Q68CP9)
I37S (p.Ile37Ser) in ARID2 (Q68CP9) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes structural context.
I37S (p.Ile37Ser) variant details
- p.Ile37Ser
- rs2137959629
- NCI-TCGA Cosmic COSV5760
- ClinGen CA384609138
- ClinVar RCV003152139
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- AlphaMissense 0.95
- MetaLR 0.27
- MetaSVM -0.60
- PolyPhen-2 0.99
- SIFT 0.14
- MutPred 0.63
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available