S22A (p.Ser22Ala) variant of ARID1A (O14497)
S22A (p.Ser22Ala) in ARID1A (O14497) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S22A (p.Ser22Ala) variant details
- p.Ser22Ala
- gnomAD 1-26696467-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.12
- MetaLR 0.02
- MetaSVM -0.87
- CADD 25.90
- PolyPhen-2 0.90
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available