K25E (p.Lys25Glu) variant of ARID1A (O14497)
K25E (p.Lys25Glu) in ARID1A (O14497) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
K25E (p.Lys25Glu) variant details
- p.Lys25Glu
- Ensembl rs2124740037
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -0.94
- CADD 23.90
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 6.9e-05)
- Structural context available