I65del (p.Ile65del) variant of ARAF (P10398)
I65del (p.Ile65del) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
I65del (p.Ile65del) variant details
- gnomAD X-47563319-CTCA-C
- Inframe Deletion
- Variant Prioritization Score for Impact Estimate 0.646
- CADD 19.40
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.305
- Literature evidence available