Y42Y (p.Tyr42Tyr) variant of ARAF (P10398)
Y42Y (p.Tyr42Tyr) in ARAF (P10398) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y42Y (p.Tyr42Tyr) variant details
- p.Tyr42Tyr
- rs755693043
- gnomAD X-47563255-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.143
- CADD 8.87
- Most common in the South Asian population (allele frequency 0.00043)
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.366
- Literature evidence available