Y24H (p.Tyr24His) variant of ARAF (P10398)
Y24H (p.Tyr24His) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y24H (p.Tyr24His) variant details
- p.Tyr24His
- gnomAD X-47563037-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- REVEL 0.68
- CADD 23.50
- PolyPhen-2 0.99
- SIFT 0.54
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.487
- Literature evidence available