V60M (p.Val60Met) variant of ARAF (P10398)
V60M (p.Val60Met) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V60M (p.Val60Met) variant details
- p.Val60Met
- gnomAD X-47563307-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- REVEL 0.59
- CADD 26.40
- PolyPhen-2 0.86
- SIFT 0.01
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score 0.0426
- Literature evidence available