T31M (p.Thr31Met) variant of ARAF (P10398)
T31M (p.Thr31Met) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, experimental measurements, and structural context.
T31M (p.Thr31Met) variant details
- p.Thr31Met
- gnomAD rs1444450941
- Missense
- Variant Prioritization Score for Impact Estimate 0.766
- REVEL 0.81
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.278