T20T (p.Thr20Thr) variant of ARAF (P10398)
T20T (p.Thr20Thr) in ARAF (P10398) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T20T (p.Thr20Thr) variant details
- p.Thr20Thr
- rs201204685
- gnomAD X-47563027-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.11
- CADD 4.13
- Most common in the 1KG:CHB population (allele frequency 0.0063)
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.623
- Literature evidence available