S44S (p.Ser44Ser) variant of ARAF (P10398)
S44S (p.Ser44Ser) in ARAF (P10398) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S44S (p.Ser44Ser) variant details
- p.Ser44Ser
- gnomAD X-47563261-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.17
- CADD 12.60
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.0372
- Literature evidence available